Table 2A: Within-batch precision and accuracy of the method for determining DAS in plasma samples.
| Batch No: 1 (n = 6) | Batch No: 2 (n = 6) | Batch No: 3 (n = 6) | |||||||
| Nominal Conc. (ng/mL) | Conc. Found (mean Results of matrix effects for dasatinib (n = 6). SD; ng/mL) | RE (%) | CV (%) | Conc. Found (mean Results of matrix effects for dasatinib (n = 6). SD; ng/mL) | RE (%) | CV (%) | Conc. Found (mean Results of matrix effects for dasatinib (n = 6). SD; ng/mL) | RE (%) | CV (%) |
| 1 (QC1) | 1.05 Results of matrix effects for dasatinib (n = 6). 0.02 | 4.65 | 2.10 | 1.00 Results of matrix effects for dasatinib (n = 6). 0.04 | 0.09 | 3.83 | 1.00 Results of matrix effects for dasatinib (n = 6). 0.05 | 0.05 | 5.08 |
| 3 (QC2) | 3.06 Results of matrix effects for dasatinib (n = 6). 0.10 | 1.93 | 3.37 | 3.01 Results of matrix effects for dasatinib (n = 6). 0.06 | 0.39 | 2.11 | 3.07 Results of matrix effects for dasatinib (n = 6). 0.02 | 2.27 | 0.71 |
| 40 (QC31) | 39.97 Results of matrix effects for dasatinib (n = 6). 0.36 | -0.08 | 0.90 | 40.03 Results of matrix effects for dasatinib (n = 6). 0.46 | 0.07 | 1.14 | 40.05 Results of matrix effects for dasatinib (n = 6). 0.38 | 0.13 | 0.94 |
| 160 (QC32) | 167.40 Results of matrix effects for dasatinib (n = 6). 1.96 | 4.63 | 1.17 | 163.03 Results of matrix effects for dasatinib (n = 6). 1.34 | 1.89 | 0.82 | 164.54 Results of matrix effects for dasatinib (n = 6). 0.75 | 2.84 | 0.45 |
| 320 (QC4) | 323.66 Results of matrix effects for dasatinib (n = 6). 4.65 | 1.14 | 1.44 | 328.08 Results of matrix effects for dasatinib (n = 6). 3.12 | 2.52 | 0.95 | 328.79 Results of matrix effects for dasatinib (n = 6). 7.02 | 2.75 | 2.14 |